Association of insulin gene VNTR INS -23/Hph1 A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children

Background Type1 diabetes mellitus (T1DM) has a multi-factorial pathogenesis; the interplay between genetic susceptibility and environmental factors is thought to provide the fundamental element for the disease. Apart from HLA, more than 50 genetic variants are associated with T1DM. INS -23/Hph1 A&g...

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Veröffentlicht in:	Egyptian Journal of Medical Human Genetics 2019-09, Vol.20 (1), p.1-6, Article 13
Hauptverfasser:	Kamel, Azza M., Mira, Marwa F., Ebid, Gamal T. A., Kassem, Samar H., Radwan, Eman R., Mamdouh, Mona, Amin, Maha, Badawy, Nora, Bazaraa, Hafez, Ibrahim, Amani, Salah, Nermine
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Children Diabetes Diabetes mellitus (insulin dependent) Environmental factors Families & family life Gene frequency Gene polymorphism Genetic diversity IDDM2 INS-23 Insulin Medicine Medicine & Public Health Minority & ethnic groups Polymorphism Restriction fragment length polymorphism Risk factors Siblings Susceptibility TIDM Type 1 Diabetes Mellitus
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