Serum ferritin and glycated hemoglobin in type 2 diabetes mellitus: A case–control study

Background: High body iron stores have been linked to insulin resistance, metabolic syndrome, and gestational diabetes. Complications of diabetes mellitus are influenced not only by its duration but also by average level of blood glucose, the latter can be monitored by glycated hemoglobin. Aim and O...

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Veröffentlicht in:National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2022-01, Vol.12 (5), p.699-702
Hauptverfasser: Manhas, Monica, Akhter, Shaheen, Sharma, Vanita, Gupta, Mrityunjay, Sachdev, Sunil
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container_issue 5
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container_title National journal of physiology, pharmacy and pharmacology
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creator Manhas, Monica
Akhter, Shaheen
Sharma, Vanita
Gupta, Mrityunjay
Sachdev, Sunil
description Background: High body iron stores have been linked to insulin resistance, metabolic syndrome, and gestational diabetes. Complications of diabetes mellitus are influenced not only by its duration but also by average level of blood glucose, the latter can be monitored by glycated hemoglobin. Aim and Objective: The aim of this study was to study the relationship of serum ferritin and glycated hemoglobin in type 2 diabetes mellitus. Materials and Methods: The case-control study was undertaken on 100 subjects, both males and females; age 35-70 years; categorized into two groups: Group 1 (Cases = 50 patients of type 2 diabetes mellitus [T2DM]) and Group 2 (Controls = 50 healthy, non-diabetic individuals). Results: Fasting blood glucose, serum ferritin, and glycated hemoglobin values were 178.96 ± 37.16 mg/dL, 261.29 ± 76.98 ng/dL, and 9.37 ± 1.44%, respectively, in T2DM cases, while the corresponding values were 95.06 ± 12.68, 90.75 ± 67.53, and 4.81 ± 0.88 in healthy controls. Conclusion: Increased levels of serum ferritin were seen in T2DM and significant correlation between blood sugar and serum ferritin was found.
doi_str_mv 10.5455/njppp.2022.12.04174202214042022
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Complications of diabetes mellitus are influenced not only by its duration but also by average level of blood glucose, the latter can be monitored by glycated hemoglobin. Aim and Objective: The aim of this study was to study the relationship of serum ferritin and glycated hemoglobin in type 2 diabetes mellitus. Materials and Methods: The case-control study was undertaken on 100 subjects, both males and females; age 35-70 years; categorized into two groups: Group 1 (Cases = 50 patients of type 2 diabetes mellitus [T2DM]) and Group 2 (Controls = 50 healthy, non-diabetic individuals). Results: Fasting blood glucose, serum ferritin, and glycated hemoglobin values were 178.96 ± 37.16 mg/dL, 261.29 ± 76.98 ng/dL, and 9.37 ± 1.44%, respectively, in T2DM cases, while the corresponding values were 95.06 ± 12.68, 90.75 ± 67.53, and 4.81 ± 0.88 in healthy controls. 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subjects Age
Blood pressure
Body mass index
Cardiovascular disease
Females
Gestational diabetes
Glucose
Hemoglobin
Hyperglycemia
Insulin resistance
Iron
Kinases
Males
Metabolic syndrome
Mortality
Proteins
Vein & artery diseases
title Serum ferritin and glycated hemoglobin in type 2 diabetes mellitus: A case–control study
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