Synthesis, structural, DNA/protein binding and cytotoxic studies of copper(I) ∝-diimine hydrazone complexes

[Display omitted] •Cu(I) complexes with α-diimine hydrazone ligands were designed, synthesized and characterized.•DNA/BSA binding and cytotoxic studies of the new Cu(I) complexes were evaluated.•The complex 4 shows better activity. A series of copper(I) complexes with α-diimine hydrazone ligands of...

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Veröffentlicht in:	Inorganica Chimica Acta 2022-04, Vol.533, p.120780, Article 120780
Hauptverfasser:	Gayathri, S., Viswanathamurthi, P., Thuslim, V., Sathya, M., Ranjani, M., Prabhakaran, R., Haribabu, J., Echeverria, Cesar
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption BSA binding Cancer Chemical analysis Coordination compounds Copper Copper(I) complexes Crystal structure CT-DNA binding Cytotoxicity Diimide Epithelium Hydrazones Ligands Mass spectrometry NMR Nuclear magnetic resonance Serum albumin Single crystals Spectral methods Synthesis Toxicity X ray analysis α-Diimine hydrazone ligands
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