Bombesin stimulates enterocyte turnover following massive small bowel resection in a rat

Recent evidence suggests that bombesin (BBS) is involved in modulation of growth and differentiation of normal small intestine. The purpose of the present study was to evaluate the effects of BBS on enterocyte turnover after massive small bowel resection in a rat. Male Sprague-Dawley rats were divid...

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Veröffentlicht in:	Pediatric surgery international 2007-05, Vol.23 (5), p.397-404
Hauptverfasser:	Sukhotnik, Igor, Slijper, Nadav, Karry, Rachel, Shaoul, Ron, Coran, Arnold G, Lurie, Michael, Shiloni, Eitan, Mogilner, Jorge G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological - drug effects Adaptation, Physiological - physiology Analysis of Variance Animals Apoptosis bcl-2-Associated X Protein - metabolism Bombesin - pharmacology Cell Proliferation - drug effects Enterocytes - drug effects Enterocytes - ultrastructure Gene expression Gene Expression - drug effects Intestinal Mucosa - drug effects Intestine, Small - drug effects Intestine, Small - surgery Intestine, Small - ultrastructure Kruskal-Wallis test Male Neurotransmitter Agents - pharmacology Organ Size - drug effects Postoperative Period Proto-Oncogene Proteins c-bcl-2 - metabolism Random Allocation Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction - methods Rodents Short Bowel Syndrome - surgery Small intestine Time Factors
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