Optogenetically engineered cell-based graphene transistor for pharmacodynamic evaluation of anticancer drugs

Rapid and effective cell-based pharmacodynamic evaluation in vitro is crucial for providing an experimental basis for the effectiveness and safety of drugs, and the existing cell-based methods for pharmacodynamics evaluation are usually invasive, dependent on chemical reagents, and/or unable to moni...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2022-05, Vol.358, p.131494, Article 131494
Hauptverfasser:	Yang, Jia, Li, Gongxin, Zu, Lipeng, Wang, Wenxue, Ge, Zhixing, Yang, Wenguang, Zhong, Ya, Zhang, Tianbiao, Zhao, Ying, Liu, Lianqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Biosensors Cancer Cancer cells Cell-based biosensor Drugs Effectiveness Electric potential Graphene Graphene transistor Nondestructive testing Optogenetics Performance evaluation Pharmacodynamic evaluation Pharmacodynamics Pharmacology Photosensitive proteins Reagents Semiconductor devices Transistors Voltage
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