Structure and biological activity of α-santonin chloro-derivatives

Structure and biological activity of α-santonin chloro-derivatives

2-Chloro-4,5α-epoxy-α-santonin and 2-chloro-α-santonin, the molecular structure of which was confirmed by an XSA, were produced by reacting α-santonin and chlorine in aqueous acetonitrile. It was found that 2-chloro-α-santonin is highly effective against trichomonas.

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Veröffentlicht in:Chemistry of natural compounds 2006-01, Vol.42 (1), p.36-40
Hauptverfasser: Ivasenko, S. A., Edil’baeva, T. T., Kulyyasov, A. T., Atazhanova, G. A., Drab, A. I., Turdybekov, K. M., Raldugin, V. A., Adekenov, S. M.
Format: Artikel
Sprache:eng
Schlagworte:
Acetonitrile
Biological activity
Chlorine
Molecular structure
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Zusammenfassung:2-Chloro-4,5α-epoxy-α-santonin and 2-chloro-α-santonin, the molecular structure of which was confirmed by an XSA, were produced by reacting α-santonin and chlorine in aqueous acetonitrile. It was found that 2-chloro-α-santonin is highly effective against trichomonas.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-006-0031-8