Small-Intestinal Metastasis from Lung Carcinoma
Abstract A 62-year-old man was referred to our hospital because of abdominal pain. Computed tomography revealed an approximately 7-cm-diameter tumor in the left abdomen with metastatic lymph nodes, an approximately 1-cm-diameter round tumor in contact with the subclavian artery in the apical lobe of...
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| Veröffentlicht in: | Case Reports in Gastroenterology 2022-03, Vol.16 (1), p.195-200 |
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| creator | Ogasawara, Naotaka Ono, Satoshi Sugiyama, Tomoya Adachi, Kazunori Yamaguchi, Yoshiharu Izawa, Shinya Ebi, Masahide Funaki, Yasushi Sasaki, Makoto Kasugai, Kunio |
| description | Abstract
A 62-year-old man was referred to our hospital because of abdominal pain. Computed tomography revealed an approximately 7-cm-diameter tumor in the left abdomen with metastatic lymph nodes, an approximately 1-cm-diameter round tumor in contact with the subclavian artery in the apical lobe of the right lung, and mediastinal lymph node enlargement in contact with the superior vena cava. Esophagogastroduodenoscopy and colonoscopy revealed no abnormalities. Double-balloon endoscopy revealed a whole circumferential ulcer in the jejunum approximately 20 cm from the ligament of Treitz. Biopsy analysis of an ulcer specimen revealed a poorly differentiated carcinoma. Immunohistochemical staining of the specimen showed that it was positive for thyroid transcription factor 1 and cytokeratin 7 and negative for cytokeratin 20, GATA-binding protein 3, caudal-type homeobox protein 2, and paired box 8. Positron emission tomography revealed positive findings in the small-intestinal tumor, nearby mesenteric lymph nodes, lymph nodes around the abdominal aorta, lung tumor, and mediastinal lymph node in the apical lobe of the right lung. Accordingly, the patient was diagnosed as having a lung carcinoma with small-intestinal metastasis (T1b, N3, M1c; cStage IVB). Pathological examination helped distinguish the primary small-intestinal tumor from the metastatic small-intestinal tumor and detect the tumor origin. |
| doi_str_mv | 10.1159/000523663 |
| format | Article |
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A 62-year-old man was referred to our hospital because of abdominal pain. Computed tomography revealed an approximately 7-cm-diameter tumor in the left abdomen with metastatic lymph nodes, an approximately 1-cm-diameter round tumor in contact with the subclavian artery in the apical lobe of the right lung, and mediastinal lymph node enlargement in contact with the superior vena cava. Esophagogastroduodenoscopy and colonoscopy revealed no abnormalities. Double-balloon endoscopy revealed a whole circumferential ulcer in the jejunum approximately 20 cm from the ligament of Treitz. Biopsy analysis of an ulcer specimen revealed a poorly differentiated carcinoma. Immunohistochemical staining of the specimen showed that it was positive for thyroid transcription factor 1 and cytokeratin 7 and negative for cytokeratin 20, GATA-binding protein 3, caudal-type homeobox protein 2, and paired box 8. Positron emission tomography revealed positive findings in the small-intestinal tumor, nearby mesenteric lymph nodes, lymph nodes around the abdominal aorta, lung tumor, and mediastinal lymph node in the apical lobe of the right lung. Accordingly, the patient was diagnosed as having a lung carcinoma with small-intestinal metastasis (T1b, N3, M1c; cStage IVB). Pathological examination helped distinguish the primary small-intestinal tumor from the metastatic small-intestinal tumor and detect the tumor origin.</description><identifier>ISSN: 1662-0631</identifier><identifier>EISSN: 1662-0631</identifier><identifier>DOI: 10.1159/000523663</identifier><identifier>PMID: 35528768</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Abdomen ; Antigens ; Breast cancer ; Cancer ; Cancer therapies ; Carcinoma ; Case reports ; Chemotherapy ; Coronary vessels ; Cytokeratin ; Endoscopy ; Gastrointestinal diseases ; Immunohistochemistry ; Keratin ; Laboratories ; Lung cancer ; Lymphatic system ; Medical prognosis ; Metastasis ; Nanoparticles ; Patients ; PET imaging ; Single Case ; Small intestine ; small-intestinal metastasis ; Thyroid gland ; Tomography ; Transcription factors ; Ulcers</subject><ispartof>Case Reports in Gastroenterology, 2022-03, Vol.16 (1), p.195-200</ispartof><rights>2022 The Author(s). Published by S. Karger AG, Basel</rights><rights>Copyright © 2022 by S. Karger AG, Basel.</rights><rights>COPYRIGHT 2022 S. Karger AG</rights><rights>2022 The Author(s). Published by S. Karger AG, Basel . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at: https://uk.sagepub.com/en-gb/eur/reusing-open-access-and-sage-choice-content</rights><rights>Copyright © 2022 by S. Karger AG, Basel 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4673-4aebe9682dfc62cce5d4d9b7344f44c36cf89a420faaae81b10764a9678e21d73</citedby><orcidid>0000-0002-9360-5134</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035918/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035918/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,27635,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35528768$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ogasawara, Naotaka</creatorcontrib><creatorcontrib>Ono, Satoshi</creatorcontrib><creatorcontrib>Sugiyama, Tomoya</creatorcontrib><creatorcontrib>Adachi, Kazunori</creatorcontrib><creatorcontrib>Yamaguchi, Yoshiharu</creatorcontrib><creatorcontrib>Izawa, Shinya</creatorcontrib><creatorcontrib>Ebi, Masahide</creatorcontrib><creatorcontrib>Funaki, Yasushi</creatorcontrib><creatorcontrib>Sasaki, Makoto</creatorcontrib><creatorcontrib>Kasugai, Kunio</creatorcontrib><title>Small-Intestinal Metastasis from Lung Carcinoma</title><title>Case Reports in Gastroenterology</title><addtitle>Case Rep Gastroenterol</addtitle><description>Abstract
A 62-year-old man was referred to our hospital because of abdominal pain. Computed tomography revealed an approximately 7-cm-diameter tumor in the left abdomen with metastatic lymph nodes, an approximately 1-cm-diameter round tumor in contact with the subclavian artery in the apical lobe of the right lung, and mediastinal lymph node enlargement in contact with the superior vena cava. Esophagogastroduodenoscopy and colonoscopy revealed no abnormalities. Double-balloon endoscopy revealed a whole circumferential ulcer in the jejunum approximately 20 cm from the ligament of Treitz. Biopsy analysis of an ulcer specimen revealed a poorly differentiated carcinoma. Immunohistochemical staining of the specimen showed that it was positive for thyroid transcription factor 1 and cytokeratin 7 and negative for cytokeratin 20, GATA-binding protein 3, caudal-type homeobox protein 2, and paired box 8. Positron emission tomography revealed positive findings in the small-intestinal tumor, nearby mesenteric lymph nodes, lymph nodes around the abdominal aorta, lung tumor, and mediastinal lymph node in the apical lobe of the right lung. Accordingly, the patient was diagnosed as having a lung carcinoma with small-intestinal metastasis (T1b, N3, M1c; cStage IVB). Pathological examination helped distinguish the primary small-intestinal tumor from the metastatic small-intestinal tumor and detect the tumor origin.</description><subject>Abdomen</subject><subject>Antigens</subject><subject>Breast cancer</subject><subject>Cancer</subject><subject>Cancer therapies</subject><subject>Carcinoma</subject><subject>Case reports</subject><subject>Chemotherapy</subject><subject>Coronary vessels</subject><subject>Cytokeratin</subject><subject>Endoscopy</subject><subject>Gastrointestinal diseases</subject><subject>Immunohistochemistry</subject><subject>Keratin</subject><subject>Laboratories</subject><subject>Lung cancer</subject><subject>Lymphatic system</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Nanoparticles</subject><subject>Patients</subject><subject>PET imaging</subject><subject>Single Case</subject><subject>Small intestine</subject><subject>small-intestinal metastasis</subject><subject>Thyroid gland</subject><subject>Tomography</subject><subject>Transcription factors</subject><subject>Ulcers</subject><issn>1662-0631</issn><issn>1662-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DOA</sourceid><recordid>eNptkdtrFDEUxoMo9uaD7yILffJh2twvL0JZal1YEWz7HM5kkjHrzGTNzAr-98ZOHVqQBBLO-X0f54LQW4IvCBHmEmMsKJOSvUDHREpaYcnIyyf_I3QyjjuMJaeMvEZHTAiqldTH6PK2h66rNsPkxykO0K2--AnGcuO4Cjn1q-1haFdryC4OqYcz9CpAN_o3j-8puv90fbf-XG2_3mzWV9vKcalYxcHX3khNm-Akdc6LhjemVozzwLlj0gVtgFMcAMBrUhOsJAcjlfaUNIqdos3s2yTY2X2OPeTfNkG0D4GUWwt5iq7zNlBulFRN8AFziYMORKs6COG1qJ1xxevj7LU_1L1vnB-mDN0z0-eZIX63bfplDWbCEF0Mzh8Ncvp5KIOyu3TIZVijpVKUNhXTuFAXM9VCqSoOIRUzV07j--jS4EMs8SuFqRBcGVMEH2aBy2kcsw9LSQTbv4u1y2IL-_5pDwv5b5MFeDcDPyC3Pi_Aoj__b3r97WYm7L4J7A9SdbGJ</recordid><startdate>20220331</startdate><enddate>20220331</enddate><creator>Ogasawara, Naotaka</creator><creator>Ono, Satoshi</creator><creator>Sugiyama, Tomoya</creator><creator>Adachi, Kazunori</creator><creator>Yamaguchi, Yoshiharu</creator><creator>Izawa, Shinya</creator><creator>Ebi, Masahide</creator><creator>Funaki, Yasushi</creator><creator>Sasaki, Makoto</creator><creator>Kasugai, Kunio</creator><general>S. 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A 62-year-old man was referred to our hospital because of abdominal pain. Computed tomography revealed an approximately 7-cm-diameter tumor in the left abdomen with metastatic lymph nodes, an approximately 1-cm-diameter round tumor in contact with the subclavian artery in the apical lobe of the right lung, and mediastinal lymph node enlargement in contact with the superior vena cava. Esophagogastroduodenoscopy and colonoscopy revealed no abnormalities. Double-balloon endoscopy revealed a whole circumferential ulcer in the jejunum approximately 20 cm from the ligament of Treitz. Biopsy analysis of an ulcer specimen revealed a poorly differentiated carcinoma. Immunohistochemical staining of the specimen showed that it was positive for thyroid transcription factor 1 and cytokeratin 7 and negative for cytokeratin 20, GATA-binding protein 3, caudal-type homeobox protein 2, and paired box 8. Positron emission tomography revealed positive findings in the small-intestinal tumor, nearby mesenteric lymph nodes, lymph nodes around the abdominal aorta, lung tumor, and mediastinal lymph node in the apical lobe of the right lung. Accordingly, the patient was diagnosed as having a lung carcinoma with small-intestinal metastasis (T1b, N3, M1c; cStage IVB). Pathological examination helped distinguish the primary small-intestinal tumor from the metastatic small-intestinal tumor and detect the tumor origin.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>35528768</pmid><doi>10.1159/000523663</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-9360-5134</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Antigens Breast cancer Cancer Cancer therapies Carcinoma Case reports Chemotherapy Coronary vessels Cytokeratin Endoscopy Gastrointestinal diseases Immunohistochemistry Keratin Laboratories Lung cancer Lymphatic system Medical prognosis Metastasis Nanoparticles Patients PET imaging Single Case Small intestine small-intestinal metastasis Thyroid gland Tomography Transcription factors Ulcers |
| title | Small-Intestinal Metastasis from Lung Carcinoma |
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