Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection

Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging depth and slow clearance from the body have impeded their use for in vivo disease detection. To address these limitations, we develop activatable polyfluorophore nanosensors with biomarker-triggered nanopart...

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Veröffentlicht in:	Nature materials 2022-05, Vol.21 (5), p.598-607
Hauptverfasser:	Huang, Jiaguo, Chen, Xiaona, Jiang, Yuyan, Zhang, Chi, He, Shasha, Wang, Hangxiang, Pu, Kanyi
Format:	Artikel
Sprache:	eng
Schlagworte:	639/925/350/59 692/308/2778 Allografts Biomarkers Biomaterials Cancer Chemistry and Materials Science Condensed Matter Physics Depolymerization Diagnosis Disease Disease detection Early Detection of Cancer Flow cytometry Fluorescence Humans In vivo methods and tests Kidney Materials Science Nanoparticles Nanosensors Nanotechnology Neoplasms Optical and Electronic Materials Pharmacokinetics Rejection Urinalysis
Online-Zugang:	Volltext
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