Tuning the Elasticity of Nanogels Improves Their Circulation Time by Evading Immune Cells

Peptide receptor radionuclide therapy is used to treat solid tumors by locally delivering radiation. However, due to nephro‐ and hepato‐toxicity, it is limited by its dosage. To amplify radiation damage to tumor cells, radiolabeled nanogels can be used. We show that by tuning the mechanical properti...

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Veröffentlicht in:Angewandte Chemie 2022-05, Vol.134 (20), p.n/a
Hauptverfasser: Desai, Prachi, Rimal, Rahul, Florea, Alexandru, Gumerov, Rustam A., Santi, Marta, Sorokina, Anastasia S., Sahnoun, Sabri E. M., Fischer, Thorsten, Mottaghy, Felix M., Morgenroth, Agnieszka, Mourran, Ahmed, Potemkin, Igor I., Möller, Martin, Singh, Smriti
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