Design, synthesis and biological evaluation of indoline derivatives as multifunctional agents for the treatment of ischemic stroke

In this work, a series of indoline derivatives as multifunctional neuroprotective agents for battling ischemic stroke were designed, synthesized, and biologically evaluated. In antioxidant assay, all compounds showed significant protective effects against H 2 O 2 -induced death of RAW 264.7 cells. I...

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Veröffentlicht in:Medicinal chemistry research 2022-05, Vol.31 (5), p.805-818
Hauptverfasser: Du, Shuaishuai, Jin, Fan, Li, Jiaming, Ma, Xiaodong, Wang, Hongwei, Qian, Shihu
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Sprache:eng
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