68Ga-TP1580 as a novel molecular probe for HER2-positive tumor imaging using MicroPET

HER2 is an attractive target for the treatment of breast cancer. 99 Tc m -labeled HER2-specific binding to the small molecule mimetic peptide B2-S22-AFA shows the potential of detecting HER2 expression in vivo (Zhang in Transl Oncol 10:518–526, 2017). However, the low resolution of SPECT-CT imaging...

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Veröffentlicht in:	Journal of radioanalytical and nuclear chemistry 2022, Vol.331 (4), p.1531-1543
Hauptverfasser:	Zhong, Jinxiu, Pan, Donghui, Guan, Yan-xing
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Chemistry Chemistry and Materials Science Computed tomography Diagnostic Radiology Gallium isotopes Hadrons Heavy Ions Image resolution Inorganic Chemistry Medical imaging Muscles Nuclear Chemistry Nuclear Physics Physical Chemistry Positron emission Purity Radiochemical analysis Radioisotopes Tomography Tumors Xenotransplantation
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