Spectrum and risk factors of growth hormone-secreting pituitary tumor combined with thyroid diseases

Objective To investigate the spectrum and clinical characteristics of growth hormone(GH)-secreting pituitary tumor combined with thyroid diseases and to analyze its risk factors. Methods A retrospective study was used to analyze 133 patients with GH-secreting pituitary tumor who underwent thyroid ultrasound examination in the Second Affiliated Hospital of Army Medical University. The patients with GH-secreting pituitary tumor were divided into thyroid abnormal group and normal thyroid group. The clinical data of the two groups were compared. The correlation between variables was analyzed by multiple linear regression, and the risk of GH-secreting pituitary tumor with thyroid disease was analyzed by binary logistic regression. Results Among the 133 GH-secreting pituitary tumor patients, 108 cases (81.2%) had thyroid diseases. (1) Classified by thyroid ultrasonography, 51 (38.3%) with nodular goiters, 44 cases (33.1%) with simple thyroid nodules, 5 cases (3.8%) with goiters, 33 cases (24.8%) without thyroid ult