Synthesis, biological evaluation and molecular docking studies of quinoline‐conjugated 1,2,3‐triazole derivatives as antileishmanial agents

In the present work, we have synthesized novel quinoline‐conjugated 1,2,3‐triazole derivatives 6a–l starting from substituted acetanilides in five steps. The synthesized compounds were screened for their antileishmanial activity. Quinoline‐conjugated 1,2,3‐triazole compounds 6c (IC50 = 15.1 μg/ml),...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2022-04, Vol.59 (4), p.739-749
Hauptverfasser:	Tapkir, Sandeep R., Patil, Rajendra H., Galave, Sharad A., Phadtare, Ganesh R., Khedkar, Vijay M., Garud, Dinesh R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical synthesis Molecular docking Quinoline Reductases Triazoles
Online-Zugang:	Volltext
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