Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant
Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination with...
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Veröffentlicht in: | Journal of perinatology 2022-04, Vol.42 (4), p.423-429 |
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description | Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination within NEC datasets has slowly improved. Additionally, quality improvement efforts are being utilized to reduce NEC through stewardship of antibiotics, acid inhibitors, central lines and blood products, as well as optimization of human milk diets. These forces are moving us to a new era, where NEC will no longer be the dominant surgical intestinal disease of the extremely preterm neonate. Indeed, in the extremely low birth weight (ELBW) population, SIP may already be the most prevalent reason for abdominal surgery. In this perspective, the reader will find supporting data and references for these assertions as well as predictions for the future. |
doi_str_mv | 10.1038/s41372-022-01347-z |
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In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination within NEC datasets has slowly improved. Additionally, quality improvement efforts are being utilized to reduce NEC through stewardship of antibiotics, acid inhibitors, central lines and blood products, as well as optimization of human milk diets. These forces are moving us to a new era, where NEC will no longer be the dominant surgical intestinal disease of the extremely preterm neonate. Indeed, in the extremely low birth weight (ELBW) population, SIP may already be the most prevalent reason for abdominal surgery. In this perspective, the reader will find supporting data and references for these assertions as well as predictions for the future.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-022-01347-z</identifier><identifier>PMID: 35177793</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/420/254 ; 692/699/1503/1581 ; Antibiotics ; Birth weight ; Breast milk ; Enterocolitis, Necrotizing - surgery ; Food contamination ; Humans ; Infant ; Infant, Extremely Low Birth Weight ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases - epidemiology ; Infant, Premature, Diseases - surgery ; Infants ; Intestinal Perforation - epidemiology ; Intestinal Perforation - etiology ; Intestinal Perforation - surgery ; Intestine ; Low birth weight ; Medicine ; Medicine & Public Health ; Optimization ; Pediatric Surgery ; Pediatrics ; Premature babies ; Premature birth ; Quality control ; Retrospective Studies ; Review Article ; Weight</subject><ispartof>Journal of perinatology, 2022-04, Vol.42 (4), p.423-429</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer Nature America, Inc.</rights><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-8108b5806fe1ccd9bab815d0b32fcf4c2f73f97d7b3140cf531961301aab8d03</citedby><cites>FETCH-LOGICAL-c342t-8108b5806fe1ccd9bab815d0b32fcf4c2f73f97d7b3140cf531961301aab8d03</cites><orcidid>0000-0002-9446-9306 ; 0000-0001-7570-0667 ; 0000-0002-7363-4640</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/s41372-022-01347-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/s41372-022-01347-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35177793$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Swanson, Jonathan R.</creatorcontrib><creatorcontrib>Hair, Amy</creatorcontrib><creatorcontrib>Clark, Reese H.</creatorcontrib><creatorcontrib>Gordon, Phillip V.</creatorcontrib><title>Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><addtitle>J Perinatol</addtitle><description>Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination within NEC datasets has slowly improved. Additionally, quality improvement efforts are being utilized to reduce NEC through stewardship of antibiotics, acid inhibitors, central lines and blood products, as well as optimization of human milk diets. These forces are moving us to a new era, where NEC will no longer be the dominant surgical intestinal disease of the extremely preterm neonate. Indeed, in the extremely low birth weight (ELBW) population, SIP may already be the most prevalent reason for abdominal surgery. In this perspective, the reader will find supporting data and references for these assertions as well as predictions for the future.</description><subject>692/420/254</subject><subject>692/699/1503/1581</subject><subject>Antibiotics</subject><subject>Birth weight</subject><subject>Breast milk</subject><subject>Enterocolitis, Necrotizing - surgery</subject><subject>Food contamination</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Extremely Low Birth Weight</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Infant, Premature, Diseases - epidemiology</subject><subject>Infant, Premature, Diseases - surgery</subject><subject>Infants</subject><subject>Intestinal Perforation - epidemiology</subject><subject>Intestinal Perforation - etiology</subject><subject>Intestinal Perforation - surgery</subject><subject>Intestine</subject><subject>Low birth weight</subject><subject>Medicine</subject><subject>Medicine & Public 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subjects | 692/420/254 692/699/1503/1581 Antibiotics Birth weight Breast milk Enterocolitis, Necrotizing - surgery Food contamination Humans Infant Infant, Extremely Low Birth Weight Infant, Newborn Infant, Premature Infant, Premature, Diseases - epidemiology Infant, Premature, Diseases - surgery Infants Intestinal Perforation - epidemiology Intestinal Perforation - etiology Intestinal Perforation - surgery Intestine Low birth weight Medicine Medicine & Public Health Optimization Pediatric Surgery Pediatrics Premature babies Premature birth Quality control Retrospective Studies Review Article Weight |
title | Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant |
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