Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant

Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination with...

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Veröffentlicht in:Journal of perinatology 2022-04, Vol.42 (4), p.423-429
Hauptverfasser: Swanson, Jonathan R., Hair, Amy, Clark, Reese H., Gordon, Phillip V.
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container_title Journal of perinatology
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creator Swanson, Jonathan R.
Hair, Amy
Clark, Reese H.
Gordon, Phillip V.
description Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or risen during the same epoch. These trends are consistent with our knowledge of the clinical arena. The ability to discern SIP contamination within NEC datasets has slowly improved. Additionally, quality improvement efforts are being utilized to reduce NEC through stewardship of antibiotics, acid inhibitors, central lines and blood products, as well as optimization of human milk diets. These forces are moving us to a new era, where NEC will no longer be the dominant surgical intestinal disease of the extremely preterm neonate. Indeed, in the extremely low birth weight (ELBW) population, SIP may already be the most prevalent reason for abdominal surgery. In this perspective, the reader will find supporting data and references for these assertions as well as predictions for the future.
doi_str_mv 10.1038/s41372-022-01347-z
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subjects 692/420/254
692/699/1503/1581
Antibiotics
Birth weight
Breast milk
Enterocolitis, Necrotizing - surgery
Food contamination
Humans
Infant
Infant, Extremely Low Birth Weight
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - epidemiology
Infant, Premature, Diseases - surgery
Infants
Intestinal Perforation - epidemiology
Intestinal Perforation - etiology
Intestinal Perforation - surgery
Intestine
Low birth weight
Medicine
Medicine & Public Health
Optimization
Pediatric Surgery
Pediatrics
Premature babies
Premature birth
Quality control
Retrospective Studies
Review Article
Weight
title Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant
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