Conditions for the Synthesis of 4,5-Diaryl-3-hydroxy-2,2'-bipyridine-6-carbonitriles by the Reaction of 1,2,4-Triazine-5-carbonitriles with 2-Aminooxazoles

Various conditions for the inverse electron-demand aza-Diels–Alder reaction in the series of 5-aryl-3-(2-pyridyl)-1,2,4-triazine-5-carbonitriles and 2-amino-4-aryloxazoles to obtain 4,5-diaryl-3-hydroxy-2,2'-bipyridine-6-carbonitriles were tested. Heating in 1,2-dichlorobenzene or under solvent...

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Veröffentlicht in:Russian journal of organic chemistry 2022-02, Vol.58 (2), p.175-179
Hauptverfasser: Rammohan, A., Krinochkin, A. P., Kopchuk, D. S., Shtaitz, Ya. K., Kovalev, I. S., Savchuk, M. I., Zyryanov, G. V., Rusinov, V. L., Chupakhin, O. N.
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container_end_page 179
container_issue 2
container_start_page 175
container_title Russian journal of organic chemistry
container_volume 58
creator Rammohan, A.
Krinochkin, A. P.
Kopchuk, D. S.
Shtaitz, Ya. K.
Kovalev, I. S.
Savchuk, M. I.
Zyryanov, G. V.
Rusinov, V. L.
Chupakhin, O. N.
description Various conditions for the inverse electron-demand aza-Diels–Alder reaction in the series of 5-aryl-3-(2-pyridyl)-1,2,4-triazine-5-carbonitriles and 2-amino-4-aryloxazoles to obtain 4,5-diaryl-3-hydroxy-2,2'-bipyridine-6-carbonitriles were tested. Heating in 1,2-dichlorobenzene or under solvent-free conditions were found to be the most effective.
doi_str_mv 10.1134/S1070428022020026
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subjects Chemistry
Chemistry and Materials Science
Diels-Alder reactions
Organic Chemistry
title Conditions for the Synthesis of 4,5-Diaryl-3-hydroxy-2,2'-bipyridine-6-carbonitriles by the Reaction of 1,2,4-Triazine-5-carbonitriles with 2-Aminooxazoles
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