Cytosolic calcium and membrane potential in articular chondrocytes during parabolic flight

Chondrocytes are the sole resident cells in articular cartilage, which line the articulating bones in joints allowing effortless movements. Chondrocytes are responsible for cartilaginous matrix synthesis, maintenance and degradation. Since these cells are frequently exposed to mechanical loading pat...

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Veröffentlicht in:	Acta astronautica 2022-04, Vol.193, p.287-302
Hauptverfasser:	Wuest, Simon L., Cerretti, Geraldine, Wadsworth, Jennifer Louise, Follonier, Cindy, Rattenbacher-Kiser, Karin F., Bradley, Timothy, Egli, Marcel, Ille, Fabian
Format:	Artikel
Sprache:	eng
Schlagworte:	Articular chondrocytes Bones Calcium Cartilage Cytosolic free calcium Data analysis Gravity Homeostasis Ion channels Mechanosensitive ion channel Membrane potential Membranes Microgravity Parabolic flight Stimuli
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