Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence

We examined the hypothesis that the dopamine D 3 receptor gene ( DRD3 ) is a susceptibility factor for cocaine dependence. The Msc I/ Bal I polymorphism of the DRD3 gene was examined in 47 Caucasian subjects with cocaine dependence and 305 Caucasian controls. Based on prior studies with a range of p...

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Veröffentlicht in:	Molecular psychiatry 1999-09, Vol.4 (5), p.484-487
Hauptverfasser:	Comings, D E, Gonzalez, N, Wu, S, Saucier, G, Johnson, P, Verde, R, MacMurray, J P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Behavioral Sciences Biological Psychology Cocaine Cocaine-Related Disorders - genetics Dopamine Dopamine D2 receptors Dopamine D3 receptors European Continental Ancestry Group - genetics Female Gene Frequency Gene polymorphism Genetic Predisposition to Disease Genotype Heterozygotes Homozygote Humans Male Medicine Medicine & Public Health Mental disorders Neurosciences original-research-article Pharmacotherapy Polymorphism, Genetic Psychiatry Receptors, Dopamine D2 - genetics Receptors, Dopamine D3 Susceptibility White people
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