Improved survival in severe acquired aplastic anemia of childhood

Multi-agent immunosuppressive therapy has produced improved survival for severe acquired aplastic anemia in children. Recently, some investigators have suggested that immunosuppressive therapy may replace bone marrow transplantation as first-line therapy for this disorder. To assess its validity, we...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2000-12, Vol.26 (11), p.1149-1156
Hauptverfasser:	Fouladi, M, Herman, R, Rolland-Grinton, M, Jones-Wallace, D, Blanchette, V, Calderwood, S, Doyle, J, Halperin, D, Leaker, M, Saunders, E F, Zipursky, A, Freedman, M H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anemia Anemia, Aplastic - drug therapy Anemia, Aplastic - mortality Anemia, Aplastic - therapy Antilymphocyte serum Aplastic anemia Bone marrow Bone Marrow Transplantation Child Child, Preschool Childhood Children Complications Cyclosporins Disorders Female Globulins Graft rejection Grafts Hemorrhage Histocompatibility antigen HLA Humans Immunosuppression Immunosuppressive agents Immunosuppressive Agents - therapeutic use Infant Male Methylprednisolone Multiagent systems Myelodysplastic syndrome Myelodysplastic syndromes Patients Pediatrics Remission Stem cell transplantation Survival Survival Rate Therapy Thymocytes Transfusion Transplantation Treatment Outcome
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