Disturbances of growth and endocrine function after busulphan-based conditioning for haematopoietic stem cell transplantation during infancy and childhood

It is generally assumed that busulphan/cyclophoshamide (Bu/Cy)-based conditioning regimens for haematopoietic stem cell transplantation (SCT) do not affect growth. We evaluated growth and endocrine function after Bu/Cy-based conditioning in 64 children without a history of irradiation. Mean height s...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2004-05, Vol.33 (10), p.1049-1056
Hauptverfasser:	BAKKER, B, OOSTDIJK, W, BRESTERS, D, WALENKAMP, M. J. E, VOSSEN, J. M, WIT, J. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibodies Antineoplastic Agents, Alkylating - therapeutic use Biological and medical sciences Body Height Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Busulfan Busulfan - therapeutic use Calcium - metabolism Child Child, Preschool Childhood Children Conditioning Disorders Disturbances Dosage and administration Endocrine gland diseases Female Growth Disorders - etiology Growth Hormone - secretion Growth hormones Hematologic Neoplasms - therapy Hematopoietic Stem Cell Transplantation - methods Hematopoietic stem cells Humans Hyperparathyroidism Hypothyroidism Immunologic Deficiency Syndromes - therapy Immunosuppressive Agents - therapeutic use Irradiation Male Medical sciences Metabolism, Inborn Errors - therapy Physiological aspects Risk factors Secretion Stem Cell Transplantation Stem cells Thyroid Thyroid diseases Thyroid gland Thyroid Gland - metabolism Thyroid Gland - pathology Time Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation Conditioning
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