The role of autologous transplantation in patients with multiple myeloma aged 65 years and over

Autologous stem cell transplantation after high-dose melphalan for the treatment with multiple myeloma has resulted in prolonged progression-free survival and overall survival in patients under 65 years. We have examined the role of autologous transplantation in 17 patients with multiple myeloma ove...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2000-03, Vol.25 (5), p.533-539
Hauptverfasser:	Sirohi, B, Powles, R, Treleaven, J, Mainwaring, P, Kulkarni, S, Pandha, H, Bhagwati, N, Horton, C, Singhal, S, Mehta, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Age Factors Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Antineoplastic Combined Chemotherapy Protocols - toxicity Autografts Bone marrow Bone marrow transplantation Busulfan Busulfan - administration & dosage Busulfan - toxicity Carmustine - administration & dosage Carmustine - toxicity Chemical and Drug Induced Liver Injury Cohort Studies Cyclophosphamide - administration & dosage Cyclophosphamide - toxicity Disease-Free Survival Doxorubicin - administration & dosage Doxorubicin - toxicity Female Graft Survival Heart Diseases - chemically induced Hematopoietic Stem Cell Mobilization Hospitalization Humans Interferons - administration & dosage Kidney Diseases - chemically induced Leukocytes (neutrophilic) Male Matched-Pair Analysis Melphalan Melphalan - administration & dosage Melphalan - toxicity Methylprednisolone - administration & dosage Methylprednisolone - toxicity Middle Aged Morbidity Multiple myeloma Multiple Myeloma - therapy Myelosuppression Neutropenia - chemically induced Neutrophils Older people Patients Platelet Count Platelets Recurrence Sepsis - chemically induced Stem cell transplantation Stem cells Survival Survival Rate Thrombocytopenia - chemically induced Transplantation Transplantation, Autologous - adverse effects Vincristine - administration & dosage Vincristine - toxicity
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