Continuous infusion idarubicin and oral busulfan as conditioning for patients with acute myeloid leukemia aged over 60 years undergoing autologous stem cell transplantation

There is growing interest in autologous stem cell transplantation (ASCT) for elderly patients with acute myeloid leukemia (AML). While mortality and toxicity from ASCT have been reduced, relapse rate is still high. In a prospective study, we investigated the feasibility of a new conditioning regimen...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2004-10, Vol.34 (7), p.573-576
Hauptverfasser:	FERRARA, F, PALMIERI, S, ANNUNZIATA, M, VIOLA, A, POCALI, B, CALIFANO, C, D'ARCO, A. M, MELE, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute myeloid leukemia Administration, Oral Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibiotics, Antineoplastic - administration & dosage Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Combined Chemotherapy Protocols - administration & dosage Autografts Biological and medical sciences Bone marrow, stem cells transplantation. Graft versus host reaction Busulfan Busulfan - administration & dosage Combined Modality Therapy Conditioning Feasibility studies Female Follow-Up Studies Gastric cancer Hematologic and hematopoietic diseases Hematopoietic Stem Cell Transplantation Humans Idarubicin - administration & dosage Infusions, Intravenous Leukemia Leukemia, Myeloid - drug therapy Leukemia, Myeloid - mortality Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukocytes (neutrophilic) Male Medical sciences Middle Aged Mortality Mucositis Older people Prospective Studies Remission Secondary Prevention Stem cell transplantation Stem cells Survival Rate Toxicity Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation Conditioning
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