Reduced efficacy of topical corticosteroid in preventing cytarabine-induced kerato-conjunctivitis in patients receiving high-dose cytarabine and total body irradiation for allogeneic hematopoietic stem cell transplantation

This study aimed to retrospectively evaluate the incidence of kerato-conjunctivitis in patients receiving TBI followed by high-dose cytarabine, and to clarify how effectively topical corticosteroid eye drops prevent kerato-conjunctivitis in these patients. Fifty-three patients who received cytarabin...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2008-08, Vol.42 (3), p.197-199
Hauptverfasser:	Mori, T, Watanabe, M, Kurotori-Sotome, T, Ito, C, Yamada, K, Yashima, T, Kobayashi, N, Kondo, S, Aisa, Y, Kato, J, Ogawa, Y, Tsubota, K, Shigematsu, N, Kubo, A, Ikeda, Y, Okamoto, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Cortex Hormones - therapeutic use Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Conjunctivitis Corticosteroids Cytarabine Cytarabine - adverse effects Diagnosis Disease prevention Diseases of cornea, anterior segment and sclera Dosage and administration Drug therapy Evaluation Eye Female Hematology Hematopoietic Stem Cell Transplantation - methods Hematopoietic stem cells Humans Internal Medicine Irradiation Keratoconjunctivitis - chemically induced Keratoconjunctivitis - etiology Leukemia - complications Male Medical sciences Medicine Medicine & Public Health Middle Aged Myelodysplastic Syndromes - complications Ophthalmology original-article Patient outcomes Prophylaxis Public Health Radiation Risk factors Sodium phosphate Stem cell transplantation Stem Cells Steroids Toxicity Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation Conditioning - adverse effects Transplantation Conditioning - methods Transplantation, Homologous Whole-Body Irradiation
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