Efficacy of an early intensification treatment integrating chemotherapy, autologous stem cell transplantation and radiotherapy for poor risk primary mediastinal large B cell lymphoma with sclerosis

The aim of our study was to evaluate the impact of an early intensification programme including chemotherapy (CHT), autologous stem cell transplantation (ASCT) and radiation therapy (RT) in patients with primary mediastinal large B cell lymphoma (MLCL) with sclerosis presenting with adverse prognost...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2002-03, Vol.29 (6), p.473-477
Hauptverfasser:	CAIROLI, R, GRILLO, G, TEDESCHI, A, GARGANTINI, L, MARENCO, P, TRESOLDI, E, BARBARANO, L, NOSARI, A. M, MORRA, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Amplification Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Autografts B-cell lymphoma Biological and medical sciences Bleomycin Bleomycin - administration & dosage Bleomycin - therapeutic use Bone marrow Bone marrow transplantation Cancer Care and treatment Chemotherapy Cisplatin Combined Modality Therapy - methods Computed tomography Cyclophosphamide Cyclophosphamide - administration & dosage Cyclophosphamide - therapeutic use Cytarabine Dexamethasone Diagnosis Doxorubicin Doxorubicin - administration & dosage Doxorubicin - therapeutic use Drug Administration Schedule Etoposide Etoposide - administration & dosage Etoposide - therapeutic use Female Hematologic and hematopoietic diseases Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Humans Induction therapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma Lymphoma, B-Cell - drug therapy Lymphoma, B-Cell - radiotherapy Lymphoma, B-Cell - surgery Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - radiotherapy Lymphoma, Large B-Cell, Diffuse - surgery Male Mediastinal Neoplasms - drug therapy Mediastinal Neoplasms - radiotherapy Mediastinal Neoplasms - surgery Medical prognosis Medical sciences Middle Aged Non-Hodgkin's lymphomas Patients Prednisone Prednisone - administration & dosage Prednisone - therapeutic use Prognosis Radiation Radiation therapy Remission Remission (Medicine) Risk Risk Factors Risk groups Sclerosis Stem cell transplantation Stem cells Thorax - drug effects Thorax - pathology Thorax - radiation effects Transplantation Transplantation, Autologous Tumors Vincristine Vincristine - administration & dosage Vincristine - therapeutic use
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