RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

Most cases of breast cancer (BrCa) mortality are due to vascular metastasis. BrCa cells must intravasate through endothelial cells (ECs) to enter a blood vessel in the primary tumor and then adhere to ECs and extravasate at the metastatic site. In this study we demonstrate that inhibition of hypoxia...

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Veröffentlicht in:	Oncogene 2012-04, Vol.31 (14), p.1757-1770
Hauptverfasser:	Zhang, H, Wong, C C L, Wei, H, Gilkes, D M, Korangath, P, Chaturvedi, P, Schito, L, Chen, J, Krishnamachary, B, Winnard, P T, Raman, V, Zhen, L, Mitzner, W A, Sukumar, S, Semenza, G L
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiopoietin Apoptosis Breast cancer Cell adhesion molecules Cell Biology Digoxin Endothelial cells Extravasation Human Genetics Hypoxia Internal Medicine Lung cancer Medicine & Public Health Metastases Metastasis Oncology original-article RNA-mediated interference Tumors
Online-Zugang:	Volltext
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