Physical and functional interaction of Runt-related protein 1 with hypoxia-inducible factor-1α

Angiogenesis and hematopoiesis are closely linked and interactive with each other, but few studies were given to identify possible links between angiogenesis-promoting proteins and hematopoiesis-related transcription factors. Here we investigated the potential relationship of oxygen-sensitive α -sub...

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Veröffentlicht in:	Oncogene 2008-01, Vol.27 (6), p.839-847
Hauptverfasser:	Peng, Z G, Zhou, M Y, Huang, Y, Qiu, J H, Wang, L S, Liao, S H, Dong, S, Chen, G Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Amino acids AML1 protein Angiogenesis Apoptosis Biological and medical sciences Cell Biology Cell differentiation Cell differentiation, maturation, development, hematopoiesis Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Deoxyribonucleic acid DNA DNA binding proteins Fundamental and applied biological sciences. Psychology Fusion protein Genetic aspects Health aspects Homology Human Genetics Hypoxia Hypoxia-inducible factor 1 Hypoxia-inducible factor 1a Internal Medicine Leukemia Medicine Medicine & Public Health Molecular and cellular biology Neovascularization Oncology original-article Properties Protein-protein interactions Proteins Runx1 protein siRNA Transcription factors Vascular endothelial growth factor
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