The expression of HMGA genes is regulated by their 3′UTR

Many benign mesenchymal tumors are characterized by chromosomal abnormalities of the regions 12q15 or 6p21.3 leading to aberrant expression of either HMGA2 (formerly HMGIC) or HMGA1 (formerly HMGIY). The proteins of both genes belong to the HMGA (formerly HMGI(Y)) family of architectural transcripti...

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Veröffentlicht in:	Oncogene 2001-07, Vol.20 (33), p.4537-4541
Hauptverfasser:	Borrmann, Lars, Wilkening, S, Bullerdiek, J
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Chromosome aberrations Cytogenetics Gene expression Mesenchyme Post-transcription Regulatory sequences Transcription factors Tumors
Online-Zugang:	Volltext
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