Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence
Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of t...
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| Veröffentlicht in: | Journal of exposure analysis and environmental epidemiology 2004-04, Vol.14 (Suppl 1), p.S65-S70 |
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| container_title | Journal of exposure analysis and environmental epidemiology |
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| creator | Kim, Hyojin Lim, Youngwook Lee, Seokju Park, Soungeun Kim, Changsoo Hong, Cheinsoo Shin, Dongchun |
| description | Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers’ urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects’ families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects’ family members were also correlated to the urinary cotinine levels of the passive smokers. |
| doi_str_mv | 10.1038/sj.jea.7500360 |
| format | Article |
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Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers’ urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects’ families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects’ family members were also correlated to the urinary cotinine levels of the passive smokers.</description><identifier>ISSN: 1559-0631</identifier><identifier>ISSN: 1053-4245</identifier><identifier>EISSN: 1559-064X</identifier><identifier>DOI: 10.1038/sj.jea.7500360</identifier><identifier>PMID: 15118747</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>Adult ; Aged ; Air Pollution, Indoor - analysis ; Biomarkers - analysis ; Chromatography, High Pressure Liquid ; Cotinine ; Cotinine - urine ; Creatinine ; Environmental effects ; Environmental Exposure ; Epidemiology ; Female ; Gas Chromatography-Mass Spectrometry ; High-performance liquid chromatography ; Housing ; Humans ; Indoor environments ; Liquid chromatography ; Male ; Medicine ; Medicine & Public Health ; Metabolites ; Middle Aged ; Nicotine ; Passive smoking ; research-article ; Sensitivity and Specificity ; Smoke ; Smoking ; Tobacco ; Tobacco smoke ; Tobacco Smoke Pollution - analysis</subject><ispartof>Journal of exposure analysis and environmental epidemiology, 2004-04, Vol.14 (Suppl 1), p.S65-S70</ispartof><rights>Springer Nature America, Inc. 2004</rights><rights>COPYRIGHT 2004 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Apr 2004</rights><rights>Nature Publishing Group 2004.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-3c3706af6e4707647c75c37aaf87b9f3d3916993a04ff0dcdfdfad533d2cfafc3</citedby><cites>FETCH-LOGICAL-c524t-3c3706af6e4707647c75c37aaf87b9f3d3916993a04ff0dcdfdfad533d2cfafc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/sj.jea.7500360$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/sj.jea.7500360$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15118747$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Hyojin</creatorcontrib><creatorcontrib>Lim, Youngwook</creatorcontrib><creatorcontrib>Lee, Seokju</creatorcontrib><creatorcontrib>Park, Soungeun</creatorcontrib><creatorcontrib>Kim, Changsoo</creatorcontrib><creatorcontrib>Hong, Cheinsoo</creatorcontrib><creatorcontrib>Shin, Dongchun</creatorcontrib><title>Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence</title><title>Journal of exposure analysis and environmental epidemiology</title><addtitle>J Expo Sci Environ Epidemiol</addtitle><addtitle>J Expo Anal Environ Epidemiol</addtitle><description>Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers’ urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects’ families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects’ family members were also correlated to the urinary cotinine levels of the passive smokers.</description><subject>Adult</subject><subject>Aged</subject><subject>Air Pollution, Indoor - analysis</subject><subject>Biomarkers - analysis</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Cotinine</subject><subject>Cotinine - urine</subject><subject>Creatinine</subject><subject>Environmental effects</subject><subject>Environmental Exposure</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>High-performance liquid chromatography</subject><subject>Housing</subject><subject>Humans</subject><subject>Indoor environments</subject><subject>Liquid chromatography</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolites</subject><subject>Middle Aged</subject><subject>Nicotine</subject><subject>Passive 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Epidemiol</stitle><addtitle>J Expo Anal Environ Epidemiol</addtitle><date>2004-04-01</date><risdate>2004</risdate><volume>14</volume><issue>Suppl 1</issue><spage>S65</spage><epage>S70</epage><pages>S65-S70</pages><issn>1559-0631</issn><issn>1053-4245</issn><eissn>1559-064X</eissn><abstract>Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers’ urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects’ families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects’ family members were also correlated to the urinary cotinine levels of the passive smokers.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>15118747</pmid><doi>10.1038/sj.jea.7500360</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Air Pollution, Indoor - analysis Biomarkers - analysis Chromatography, High Pressure Liquid Cotinine Cotinine - urine Creatinine Environmental effects Environmental Exposure Epidemiology Female Gas Chromatography-Mass Spectrometry High-performance liquid chromatography Housing Humans Indoor environments Liquid chromatography Male Medicine Medicine & Public Health Metabolites Middle Aged Nicotine Passive smoking research-article Sensitivity and Specificity Smoke Smoking Tobacco Tobacco smoke Tobacco Smoke Pollution - analysis |
| title | Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence |
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