Galactorrhea with metoclopramide use in the neonatal unit

We report a 3½-month-old infant with trisomy 21 presenting with galactorrhea in the neonatal intensive care unit (NICU). Endocrine work-up showed a high prolactin level (64.4 ng ml −1 —normal: 0.5 to 30 ng ml −1 ). Cessation of therapy with metoclopramide (0.2 mg kg −1 per dose q 6 h) resulted in the resolution of galactorrhea with a decrease in serum prolactin level (20.1 ng ml −1 ). We present this case to highlight this uncommon side effect of a commonly used medication in the NICU.