Protective effects of cyclodextrins on edaravone degradation induced by atmospheric oxygen or additive oxidant

Antioxidants scavenge free radicals and may help prevent disease. However, due to poor stability, continuous intake is required. This study investigates the ability of cyclodextrin inclusion to improve the stability of the novel antioxidant edaravone. Kinetic models of cyclodextrin protection agains...

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Veröffentlicht in:	Journal of inclusion phenomena and macrocyclic chemistry 2022-04, Vol.102 (3-4), p.327-338
Hauptverfasser:	Hiroshige, Ryosuke, Goto, Satoru, Ichii, Risa, Shimizu, Shota, Wada-Hirai, Ayako, Li, Ying-Peng, Shimada, Yohsuke, Otsuka, Yuta, Makino, Kosho, Takahashi, Hideyo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Atmospheric models Bioavailability Chemistry Chemistry and Materials Science Complexation Crystallography and Scattering Methods Cyclodextrins Food Science Free radicals Organic Chemistry Original Article Oxidation rate Oxidizing agents Scatchard curves Stability
Online-Zugang:	Volltext
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