Fetal Neuroprotective Mechanism of Maternal Magnesium Sulfate: Proteomic Analysis

Mg supplementation has been shown to protect preterm fetuses from white and gray matter damage, but the mechanism is unclear. The purpose of this study was to study the effect of maternal inflammation on the overall protein panel of the fetal rat brain, as well as the neuroprotective effect of magne...

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Veröffentlicht in:	Journal of molecular neuroscience 2022-03, Vol.72 (3), p.626-632
Hauptverfasser:	Reicher, Lee, Dabaja, Hanin, Ginsberg, Yuval, Khatib, Nizar, Fouks, Yuval, Attali, Emmanuel, Ross, Michael G., Weiner, Zeev, Beloosesky, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Brain Brain - metabolism Brain injury Cell Biology Complement component C3 Cytokines Female Fetus Fetuses Glutathione Glutathione transferase Head injuries Inflammation Ischemia Kinases Lipopolysaccharides Lipopolysaccharides - pharmacology Magnesium sulfate Magnesium Sulfate - pharmacology Magnesium Sulfate - therapeutic use MAP kinase Metallothionein Neurochemistry Neurology Neuroprotection Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Neurosciences Neurotoxicity Oligodendrocytes Pregnancy Protein kinase Proteins Proteomics Rats Rats, Sprague-Dawley Substantia grisea Sulfates Supplements α2-Macroglobulin
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