Changes in the Metabolism of Sphingomyelin and Ceramide in the Brain Structures and Spinal Cord of Transgenic Mice (FUS(1-359)) Modeling Amyotrophic Lateral Sclerosis

Changes in the expression of genes for enzymes of sphingolipid metabolism in transgenic FUS mice (FUS (1-359)) simulating amyotrophic lateral sclerosis (ALS) were found. The profiles of molecular species of sphingomyelins (SM) and ceramides (CER) in the structure of the brain and in the spinal cord...

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Veröffentlicht in:	Russian journal of bioorganic chemistry 2022-02, Vol.48 (1), p.178-189
Hauptverfasser:	Shupik, M. A., Gutner, U. A., Ustyugov, A. A., Rezvykh, A. P., Funikov, S. Yu, Maloshitskaya, O. A., Sokolov, S. A., Lebedev, A. T., Alessenko, A. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Brain Enzymes Gene expression Life Sciences Metabolism Organic Chemistry Pathogenesis Spinal cord
Online-Zugang:	Volltext
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