Assessments of Conditional and Unconditional Type I Error Probabilities for Bayesian Hypothesis Testing with Historical Data Borrowing

Applications of Bayesian designs allow the borrowing of the strength of historical information and become more and more attractive in new drug developments. Nonetheless, according to the FDA guidance issued in 2020, Bayesian designs are classified as complex innovative designs that have rarely been...

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Veröffentlicht in:	Statistics in biosciences 2022-04, Vol.14 (1), p.139-157
Hauptverfasser:	Quan, Hui, Chen, Xiaofei, Chen, Xun, Luo, Xiaodong
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayesian analysis Biostatistics Control data (computers) Health Sciences Hypothesis testing Mathematics and Statistics Medicine Normal distribution Normality Statistical analysis Statistics Statistics for Life Sciences Theoretical Ecology/Statistics
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