Long-term chronic caloric restriction alters miRNA profiles in the brain of ageing mice

Calorie restriction (CR) has been shown to be one of the most effective methods in alleviating the effects of ageing and age-related diseases. Although the protective effects of CR have been reported, the exact molecular mechanism still needs to be clarified. This study aims to determine differentia...

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Veröffentlicht in:	British journal of nutrition 2022-03, Vol.127 (5), p.641-652
Hauptverfasser:	Ozorhan, Umit, Tuna, Bilge G., Cicekdal, Munevver B., Kuskucu, Aysegul, Bayrak, Omer F., Yilmaz, Bayram, Demirel, Pinar B., Cleary, Margot P., Dogan, Soner
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age related diseases Aging Aging - physiology Animal cognition Animals Brain Brain - metabolism Brain research Caloric Restriction - methods Chromatin Chronic illnesses Cognitive ability Dietary restrictions DNA methylation DNA microarrays Food Gene expression Growth factors Histones Mice Mice, Inbred ICR MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Molecular Nutrition Neurodegeneration Neurogenesis Nutrient deficiency Ontology Physiology Traumatic brain injury
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