Oculocutaneous albinism in a wild koala (Phascolarctos cinereus) with unusual renal impairment

An albino koala with progressive weight loss was submitted twice to a wildlife clinic. Due to poor prognosis, the koala was euthanised. Relevant histopathology findings include a membranous glomerulopathy and renal ceroid lipofuscinosis. Transmission electron microscopy revealed thickening of the me...

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Veröffentlicht in:Veterinary record case reports 2021-03, Vol.9 (1), p.n/a
Hauptverfasser: Gonzalez‐Astudillo, Viviana, Palmieri, Chiara, Shaw, Stephanie, Allavena, Rachel
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Sprache:eng
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Zusammenfassung:An albino koala with progressive weight loss was submitted twice to a wildlife clinic. Due to poor prognosis, the koala was euthanised. Relevant histopathology findings include a membranous glomerulopathy and renal ceroid lipofuscinosis. Transmission electron microscopy revealed thickening of the mesangial matrix and glomerular basement membrane and a few dense deposits suggestive of a chronic nephropathy. Albinism in koalas is rare, and this report describes general features of wildlife albinism as well as drawing a comparison to a well‐described amelanotic syndrome in humans that typically results in a severe glomerulopathy due to circulating or in situ immune complexes.
ISSN:2052-6121
2052-6121
DOI:10.1002/vrc2.42