A small and highly sensitive red/far-red optogenetic switch for applications in mammals

Optogenetic technologies have transformed our ability to precisely control biological processes in time and space. Yet, current eukaryotic optogenetic systems are limited by large or complex optogenetic modules, long illumination times, low tissue penetration or slow activation and deactivation kine...

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Veröffentlicht in:	Nature biotechnology 2022-02, Vol.40 (2), p.262-272
Hauptverfasser:	Zhou, Yang, Kong, Deqiang, Wang, Xinyi, Yu, Guiling, Wu, Xin, Guan, Ningzi, Weber, Wilfried, Ye, Haifeng
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/1511 631/1647/2253 631/553/552 631/61/185 Agriculture Animals Arabidopsis - genetics Arabidopsis Proteins - genetics Bioinformatics Biological activity Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology CRISPR Deactivation Diabetes mellitus Epigenetics Extracellular signal-regulated kinase Homeostasis Illumination Insulin Kinases Life Sciences Light Light emitting diodes Mammals MAP kinase Mice Microcapsules Nuclease Optogenetics Phytochrome A - genetics Phytochrome A - metabolism Protein kinase Proteins Rabbits Rats Transgenes
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