Outcomes of sequestrectomy and buccal fat pad reconstruction in the management of medication-related osteonecrosis of the jaws
The aim of the study was to evaluate the effectiveness of buccal fat pad (BFP) in the reconstruction of surgical defects following sequestrectomy in medication-related osteonecrosis of the jaws (MRONJ). A total of ten patients with MRONJ underwent sequestrectomy and reconstruction using BFP. There w...
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| Veröffentlicht in: | Oral and maxillofacial surgery 2022-03, Vol.26 (1), p.147-153 |
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| creator | Jose, Anson Rawat, Aditi Nagori, Shakil Ahmed Arya, Saurav Shukla, Deepak |
| description | The aim of the study was to evaluate the effectiveness of buccal fat pad (BFP) in the reconstruction of surgical defects following sequestrectomy in medication-related osteonecrosis of the jaws (MRONJ). A total of ten patients with MRONJ underwent sequestrectomy and reconstruction using BFP. There were 3 males and 7 females. The age range was 20–70 years. Two patients were diagnosed with stage 2, and eight patients were diagnosed with stage 3 disease. Eight defects were present in the maxilla and two in the posterior mandible. Oro-antral communication was present in 8 cases. All patients have undergone sequestrectomy, debridement and reconstruction using BFP under local anaesthesia. Postoperatively, the patients were followed up at 1, 3, 6 and 12 months and evaluated for complete epithelisation of defect, infection, pain and recurrence of the lesion. Complete epithelisation with closure of the defect was achieved in all the cases. None of the patients had residual pain or inflammation at the surgical site. There was no case of postoperative infection. Reconstruction using buccal fat pad is an effective treatment modality to provide symptomatic relief and to prevent further progression of disease in MRONJ patients. |
| doi_str_mv | 10.1007/s10006-021-00973-9 |
| format | Article |
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A total of ten patients with MRONJ underwent sequestrectomy and reconstruction using BFP. There were 3 males and 7 females. The age range was 20–70 years. Two patients were diagnosed with stage 2, and eight patients were diagnosed with stage 3 disease. Eight defects were present in the maxilla and two in the posterior mandible. Oro-antral communication was present in 8 cases. All patients have undergone sequestrectomy, debridement and reconstruction using BFP under local anaesthesia. Postoperatively, the patients were followed up at 1, 3, 6 and 12 months and evaluated for complete epithelisation of defect, infection, pain and recurrence of the lesion. Complete epithelisation with closure of the defect was achieved in all the cases. None of the patients had residual pain or inflammation at the surgical site. There was no case of postoperative infection. Reconstruction using buccal fat pad is an effective treatment modality to provide symptomatic relief and to prevent further progression of disease in MRONJ patients.</description><identifier>ISSN: 1865-1550</identifier><identifier>EISSN: 1865-1569</identifier><identifier>DOI: 10.1007/s10006-021-00973-9</identifier><identifier>PMID: 34028628</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acids ; Adipose Tissue - transplantation ; Adult ; Aged ; Bisphosphonate-Associated Osteonecrosis of the Jaw - surgery ; Bisphosphonates ; Cheek - surgery ; Communication ; Debridement ; Defects ; Female ; Humans ; Infections ; Jaw ; Local anesthesia ; Male ; Mandible ; Maxillofacial surgery ; Medicine ; Medicine & Public Health ; Middle Aged ; Oral and Maxillofacial Surgery ; Original Article ; Pain ; Patients ; Surgical Flaps ; Young Adult</subject><ispartof>Oral and maxillofacial surgery, 2022-03, Vol.26 (1), p.147-153</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021</rights><rights>2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-p180t-d276eba83ff68aeadd1644e0e24e5cc952a9133699c5834f092b24f4728810f63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10006-021-00973-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10006-021-00973-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34028628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jose, Anson</creatorcontrib><creatorcontrib>Rawat, Aditi</creatorcontrib><creatorcontrib>Nagori, Shakil Ahmed</creatorcontrib><creatorcontrib>Arya, Saurav</creatorcontrib><creatorcontrib>Shukla, Deepak</creatorcontrib><title>Outcomes of sequestrectomy and buccal fat pad reconstruction in the management of medication-related osteonecrosis of the jaws</title><title>Oral and maxillofacial surgery</title><addtitle>Oral Maxillofac Surg</addtitle><addtitle>Oral Maxillofac Surg</addtitle><description>The aim of the study was to evaluate the effectiveness of buccal fat pad (BFP) in the reconstruction of surgical defects following sequestrectomy in medication-related osteonecrosis of the jaws (MRONJ). 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A total of ten patients with MRONJ underwent sequestrectomy and reconstruction using BFP. There were 3 males and 7 females. The age range was 20–70 years. Two patients were diagnosed with stage 2, and eight patients were diagnosed with stage 3 disease. Eight defects were present in the maxilla and two in the posterior mandible. Oro-antral communication was present in 8 cases. All patients have undergone sequestrectomy, debridement and reconstruction using BFP under local anaesthesia. Postoperatively, the patients were followed up at 1, 3, 6 and 12 months and evaluated for complete epithelisation of defect, infection, pain and recurrence of the lesion. Complete epithelisation with closure of the defect was achieved in all the cases. None of the patients had residual pain or inflammation at the surgical site. There was no case of postoperative infection. 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| subjects | Acids Adipose Tissue - transplantation Adult Aged Bisphosphonate-Associated Osteonecrosis of the Jaw - surgery Bisphosphonates Cheek - surgery Communication Debridement Defects Female Humans Infections Jaw Local anesthesia Male Mandible Maxillofacial surgery Medicine Medicine & Public Health Middle Aged Oral and Maxillofacial Surgery Original Article Pain Patients Surgical Flaps Young Adult |
| title | Outcomes of sequestrectomy and buccal fat pad reconstruction in the management of medication-related osteonecrosis of the jaws |
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