Immune response of C57BL/6J mice to herpes zoster subunit vaccines formulated with nanoemulsion-based and liposome-based adjuvants

•An MF59-adjuvanted gE subunit vaccine induced an improved immune response compared to gE alone.•MF59 elicited an increased but relatively limited production of Th1 and Th2 cytokines.•MF59/QS-21 and MF59/CpG 2006 were more effective than MF59 in improving immunity.•MF59/QS-21 and MF59/CpG 2006 elici...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International immunopharmacology 2021-12, Vol.101 (Pt B), p.108216, Article 108216
Hauptverfasser:	He, Lei, Sun, Bo, Guo, Yingnan, Yan, Kunming, Liu, Dawei, Zang, Yang, Jiang, Chunlai, Zhang, Yong, Kong, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant Adjuvants Adjuvants, Immunologic Animals Antibodies Antibodies, Viral - blood Antibodies, Viral - classification Antigens Body temperature Body weight Cell-mediated immunity CpG islands Cytokines Durability Emulsions Enzyme-linked immunosorbent assay Female Glycoprotein E Glycoproteins Herpes zoster Herpes Zoster - prevention & control Humoral immunity IgG antibody Immune response Immune response (cell-mediated) Immune system Immunoglobulin G Immunoglobulin G - blood Interferon Interferon-gamma Interleukin 10 Interleukin 2 Interleukin 4 Liposomes Lymphocytes T Mice Mice, Inbred C57BL Nanoemulsions Nanostructures Nervous tissues Protein Subunits Recurrent infection Spleen - cytology Splenocytes Subunit vaccine Vaccines Varicella Viral Proteins - immunology Viral Vaccines - immunology Viruses γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!