The Risk of Preoperative Central Nervous System-Acting Medications on Delirium Following Hip or Knee Surgery: A Matched Case-Control Study

Introduction Medicines acting on the central nervous system can increase the risk of postoperative delirium, but the specific medicines associated with greatest risk remain unclear. Objectives We aimed to examine the risk of individual central nervous system-acting medicines used preoperatively on d...

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Veröffentlicht in:	Drug safety 2022, Vol.45 (1), p.75-82
Hauptverfasser:	Kassie, Gizat M., Roughead, Elizabeth E., Nguyen, Tuan A., Pratt, Nicole L., Kalisch Ellett, Lisa M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Analgesics Antidepressants Antidepressive Agents - adverse effects Anxiolytics Australia - epidemiology Benzodiazepines Case-Control Studies Central Nervous System Citalopram Codes Confidence intervals Delirium Delirium - chemically induced Delirium - epidemiology Dementia Drug Safety and Pharmacovigilance Ethics Exposure Fluvoxamine Fractures Hip Hospitalization Hospitals Humans Hypnotics Joint surgery Knee Medicine Medicine & Public Health Mental disorders Mirtazapine Mortality Narcotics Nervous system Nitrazepam Older people Opioids Original Research Article Patients Pharmacology/Toxicology Population Psychotropic drugs Risk Risk Factors Sedatives Sertraline Socioeconomic factors Surgery Systematic review Venlafaxine Venlafaxine Hydrochloride
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