Retracted: Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling

There is an urgent need to make cisplatin (cDDP) more effective and less toxic in the treatment of ovarian cancer for its systemic side effects and high resistance rate. In this study, we investigated the effect of quercetin (Qu) pretreatment on the potentiation of cDDP in ovarian cancer. We found t...

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Veröffentlicht in:	The FEBS journal 2015-03, Vol.282 (6), p.1111-1125
Hauptverfasser:	Yang, Zongyuan, Liu, Yi, Liao, Jing, Gong, Cheng, Sun, Chaoyang, Zhou, Xiaoshui, Xiao, Wei, Zhang, Taoran, Gao, Qinglei, Ding, Ma, Chen, Gang
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Anticancer properties Antitumor activity Apoptosis Cancer Chemosensitization Cisplatin Creatinine Cytotoxicity Endoplasmic reticulum High resistance Kidneys Ovarian cancer Phosphorylation Pretreatment Quercetin Side effects Signal transduction Signaling Stat3 protein Tauroursodeoxycholic acid Toxicity Tumors Xenografts Xenotransplantation
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