Synthesis of Indoline‐Fused 2,5‐Diketopiperazine Scaffolds via Ugi‐4CR in the Basic Mediated Tandem Consecutive Cyclization

This study has developed a method to prepare diastereo‐ and regio‐selective indoline‐fused 2,5‐diketopiperazine scaffolds. The synthetic process involved an Ugi four‐component reaction in which readily available starting materials were used and a metal‐free intramolecular post‐Ugi tandem consecutive...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Advanced synthesis & catalysis 2021-11, Vol.363 (21), p.4960-4968
Hauptverfasser:	Wu, Chih‐Yu, Murugan, Sivan Perumal, Wang, Yu‐Wei, Pan, Hao‐Wei, Sun, Bing‐Jian, Lin, Yu‐Ting, Fatimah, Siti, Chang, Agnes H. H., Chen, Chinpiao, Lee, Gene‐Hsian
Format:	Artikel
Sprache:	eng
Schlagworte:	2,5-Diketopiperazine Crystal structure Cyclization Density functional theory Indoline-fused 2,5-Diketopiperazine Multicomponent reactions Post-Ugi transformation Scaffolds Substrates Ugi-4CR
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!