Synthesis, antiproliferative, and antimicrobial properties of novel phthalimide derivatives

In this research, a series of new phthalimide derivatives with disulfide bonds were designed and synthesized, and their in vitro antiproliferative activities against normal cell lines L929, human cancer cells Hela, MCF-7, and A549 were assessed via the CCK-8 assay. At the same time, in vitro antimic...

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Veröffentlicht in:	Medicinal chemistry research 2022, Vol.31 (1), p.120-131
Hauptverfasser:	Chi, Chun-Lan, Xu, Lu, Li, Jun-Jie, Liu, Yang, Chen, Bao-Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Anticancer properties Antiinfectives and antibacterials Antimicrobial activity Antimicrobial agents Antiproliferatives Biochemistry Biological effects Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cell proliferation Cholecystokinin Disulfide bonds E coli Escherichia coli HeLa cells Inorganic Chemistry Medicinal Chemistry Original Research Pharmacology/Toxicology Phthalimide Phthalimides Staphylococcus aureus Tumor cell lines
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