Cediranib, a pan-inhibitor of vascular endothelial growth factor receptors, inhibits proliferation and enhances therapeutic sensitivity in glioblastoma cells

Aims Glioblastoma (GB) is the most aggressive type of brain tumor. Rapid progression, active angiogenesis, and therapy resistance are major reasons for its high mortality. Elevated expression of members of the vascular endothelial growth factor (VEGF) family suggests that anti-VEGF therapies may be...

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Veröffentlicht in:Life sciences (1973) 2021-12, Vol.287, p.1
Hauptverfasser: Momeny, Majid, Shamsaiegahkani, Sahar, Kashani, Bahareh, Hamzehlou, Sepideh, Esmaeili, Fatemeh, Yousefi, Hassan, Irani, Shiva, Mousavi, Seyed A, Ghaffari, Seyed H
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