Impact of cisplatin administration on cerebellar cortical structure and locomotor activity of infantile and juvenile albino rats: the role of oxidative stress

The central neurotoxicity of cisplatin (CisPt) has always raised questions especially during development, but few studies are available. Hence, this work was designed to assess the CisPt’s impacts on the postnatal rat cerebellum via evaluation of locomotor activity, histological and immunohistochemi...

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Veröffentlicht in:	Anatomical science international 2022, Vol.97 (1), p.30-47
Hauptverfasser:	Mokhtar, Hanan E. L., Hulail, Mohey A. E., Mahmoud, Samar Mortada, Yousef, Doaa Mohammed
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy Animal Anatomy Animal Physiology Animals Antioxidants Cell Biology Cell migration Cell proliferation Cerebellar Cortex Cerebellum Chemotherapy Cisplatin Cisplatin - toxicity Glial fibrillary acidic protein Gliosis Hemorrhage Histology Human Physiology Juveniles Lipid peroxidation Localization Locomotion Locomotor activity Medicine Medicine & Public Health Morphology Motor activity Neurosciences Neurotoxicity Original Article Oxidative Stress Purkinje cells Rats Rats, Wistar
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