Engineering a Non‐Natural Photoenzyme for Improved Photon Efficiency

Photoenzymes are biological catalysts that use light to convert starting materials into products. These catalysts require photon absorption for each turnover, making quantum efficiency an important optimization parameter. Flavin‐dependent “ene”‐reductases (EREDs) display latent photoenzymatic activi...

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Veröffentlicht in:	Angewandte Chemie 2022-01, Vol.134 (2), p.n/a
Hauptverfasser:	Nicholls, Bryce T., Oblinsky, Daniel G., Kurtoic, Sarah I., Grosheva, Daria, Ye, Yuxuan, Scholes, Gregory D., Hyster, Todd K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption spectroscopy Amides biocatalysis Catalysts Chemical synthesis Chemistry directed evolution Efficiency Engineering Flavin Mutation Optimization photocatalysis Photon absorption Photons photophysics Protein engineering Proteins Quantum efficiency Reductases transient absorption
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