Birch Reduction of Arenes Using Sodium Dispersion and DMI under Mild Conditions
An easy-to-handle sodium dispersion in paraffin oil (SD), in combination with inexpensive and environmentally benign 1,3-dimethyl-2-imidazolidinone (DMI) as an additive enables the Birch-type reduction of a variety of arenes with high yields, selectivity, and tolerance of functionality such as ether...
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Veröffentlicht in: | Chemistry letters 2022-01, Vol.51 (1), p.38-40 |
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creator | Asako, Sobi Takahashi, Ikko Kurogi, Takashi Murakami, Yoshiaki Ilies, Laurean Takai, Kazuhiko |
description | An easy-to-handle sodium dispersion in paraffin oil (SD), in combination with inexpensive and environmentally benign 1,3-dimethyl-2-imidazolidinone (DMI) as an additive enables the Birch-type reduction of a variety of arenes with high yields, selectivity, and tolerance of functionality such as ether, alcohol, amine, amide, and carboxylic acid. |
doi_str_mv | 10.1246/cl.210546 |
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source | Oxford University Press Journals All Titles (1996-Current) |
subjects | Aromatic compounds Carboxylic acids Dispersion Paraffins Reduction Selectivity Sodium |
title | Birch Reduction of Arenes Using Sodium Dispersion and DMI under Mild Conditions |
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