An RCT of acute health effects in COPD-patients after passive vape exposure from e-cigarettes

An RCT of acute health effects in COPD-patients after passive vape exposure from e-cigarettes

Background: E-cigarette use has been shown to have short-term acute effects among active users but less is known of the acute passive effects, particularly among individuals with existing respiratory diseases. Objective: To investigate local and systemic effects of short-term passive vape exposure a...

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Veröffentlicht in:European clinical respiratory journal 2021-01, Vol.8 (1), p.1861580
Hauptverfasser: Rosenkilde Laursen, Karin, Bønløkke, Jakob Hjort, Bendstrup, Elisabeth, Bilde, Merete, Glasius, Marianne, Heitmann Gutzke, Vibeke, Puthukkadan Moosakutty, Shamjad, Olin, Anna-Carin, Ravn, Peter, Østergaard, Kirsten, Sigsgaard, Torben
Format: Artikel
Sprache:eng
Schlagworte:
Chronic obstructive pulmonary disease
COPD
Electronic cigarettes
Electronic nicotine delivery systems
exposure
human
human exposure
Lungmedicin och allergi
particulate matter
Proteins
RCT
Respiratory Medicine and Allergy
Respiratory System
secondhand vape
spirometry
Vaping
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Zusammenfassung:Background: E-cigarette use has been shown to have short-term acute effects among active users but less is known of the acute passive effects, particularly among individuals with existing respiratory diseases. Objective: To investigate local and systemic effects of short-term passive vape exposure among patients with mild or moderate chronic obstructive pulmonary disease (COPD). Methods: In a double-blinded crossover study 16 non-smoking COPD-patients (mean age 68) were randomly exposed for 4 h to passive vape (median PM 2.5 : 18 µg/m 3 (range: 8-333)) and clean air (PM 2.5  
ISSN:2001-8525
2001-8525
DOI:10.1080/20018525.2020.1861580