Biologically active acylthioureas and their Ni(II) and Cu(II) Complexes: Structural, spectroscopic, anti-proliferative, nucleolytic and antimicrobial studies

[Display omitted] •Ni(II) and Cu(II) complexes of benzoylthiourea ligands were synthesized and characterized.•The square-planar Ni(II) and Cu(II) complexes exhibited cis-trans isomerism.•Compounds exhibited appreciable antimicrobial and DNA binding properties.•Cu(II) complex of the morpholine deriva...

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Veröffentlicht in:	Inorganica Chimica Acta 2021-12, Vol.528, p.120590, Article 120590
Hauptverfasser:	Oyeka, Ebube E., Babahan, Ilknur, Eboma, Bernard, Ifeanyieze, Kenechukwu J., Okpareke, Obinna C., Coban, Esin P., Özmen, Ali, Coban, Burak, Aksel, Mehran, Özdemir, Namık, Groutso, Tatiana.V., Ayogu, Jude I., Yildiz, Ufuk, Dinçer Bilgin, Mehmet, Halil Biyik, H., Schrage, Briana R., Ziegler, Christopher J., Asegbeloyin, Jonnie N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer Anticancer properties Antiinfectives and antibacterials Antimicrobial Antimicrobial agents Antiproliferatives Apoptosis Bacteria Binding Breast cancer (MCF-7) Cancer Cell death Complexation Complexes Coordination compounds Copper Crystal structure DNA binding Gram-positive bacteria Morpholine Nickel Prostate cancer (PC-3) Single crystals Spectroscopic analysis Thiourea Thioureas X-ray diffraction
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