Diverse landscape of dermatologic toxicities from small‐molecule inhibitor cancer therapy

Background Advances in molecular biology and genetics have contributed to breakthrough treatments directed at specific pathways associated with the development of cancer. Small‐molecule inhibitors (Nibs) aimed at a variety of cellular pathways have been efficacious; however, they are associated with...

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Veröffentlicht in:	Journal of cutaneous pathology 2022-01, Vol.49 (1), p.61-81
Hauptverfasser:	Seervai, Riyad N. H., Cho, Woo Cheal, Chu, Emily Y., Marques‐Piubelli, Mario L., Ledesma, Debora A., Richards, Kristen, Heberton, Meghan M., Nelson, Kelly C., Nagarajan, Priyadharsini, Torres‐Cabala, Carlos A., Prieto, Victor G., Curry, Jonathan L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Cancer therapies Cell division Clinical trials dermatologic toxicities DNA repair Drug Eruptions - metabolism Drug Eruptions - pathology Enzyme Inhibitors - adverse effects Enzyme Inhibitors - therapeutic use Humans Inflammation Kinases Literature reviews Neoplasia Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - pathology Protein-tyrosine kinase Signal transduction small‐molecule inhibitors Squamous cell carcinoma targeted cancer therapy
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