In Vitro and In Silico Evaluations of Anti-Mycobacterium tuberculosis Activity of Benzohydrazones Compounds

Tuberculosis is a disease caused by Mycobacterium tuberculosis , with high mortality rates and an extended treatment that causes severe adverse effects, besides the emergence of resistant bacteria. Therefore, the search for new compounds with anti- M. tuberculosis activity has considerably increased...

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Veröffentlicht in:	Microbial drug resistance (Larchmont, N.Y.) N.Y.), 2021-11, Vol.27 (11), p.1564-1577
Hauptverfasser:	Sampiron, Eloísa Gibin, Costacurta, Giovana Ferreira, Calsavara, Leonora Lacerda, Baldin, Vanessa Pietrowski, Silva, Gabrielle Vaz da, Alves Olher, Vanessa Guimarães, Ferraretto, Lincoln Herholz, Caleffi-Ferraciolli, Katiany Rizzieri, Cardoso, Rosilene Fressatti, Siqueira, Vera Lucia Dias, Vandresen, Fábio, Scodro, Regiane Bertin de Lima
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Antitubercular Agents - pharmacology Assaying Blood-brain barrier Cytotoxicity Efflux Fungicides Hydrazones - pharmacology Mechanisms Microbial Sensitivity Tests Minimum inhibitory concentration Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Toxicity Tuberculosis
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