“Left-hand strategy” for the design, synthesis and discovery of novel triazole–mercaptobenzothiazole hybrid compounds as potent quorum sensing inhibitors and anti-biofilm formation of Pseudomonas aeruginosa

Herein, a library of novel hybrid 6-(4-substituted-1 H -1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles was designed using a “left-hand strategy” and synthesized using microwave-assisted synthesis. The synthesized compounds were screened against quorum sensing activities and biofilm formation of Gram-n...

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Veröffentlicht in:	New journal of chemistry 2021-11, Vol.45 (46), p.21631-21637
Hauptverfasser:	Tung, Truong Thanh, Xuan, Huy Luong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biofilms Biological effects Mercaptobenzothiazole Pseudomonas aeruginosa Synthesis Virulence
Online-Zugang:	Volltext
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